Regenerative medicine has revolutionized how we treat musculoskeletal injuries in horses. These biologic therapies harness the horse’s own healing capabilities to promote tissue repair and reduce inflammation.
Platelet-Rich Plasma (PRP)
PRP is prepared by collecting a blood sample from the horse and concentrating the platelets through centrifugation. The resulting product is rich in growth factors that promote tissue healing.
Common uses:
- Tendon and ligament injuries
- Wound healing
- Joint therapy
PRP is typically injected directly into the injured tissue under ultrasound guidance. Most protocols involve one to three treatments depending on the injury severity and response.
IRAP (Interleukin-1 Receptor Antagonist Protein)
IRAP is an autologous conditioned serum that targets the inflammatory cascade within joints. Blood is incubated with specialized beads that stimulate the production of anti-inflammatory proteins.
Common uses:
- Osteoarthritis
- Synovitis
- Joint inflammation
IRAP is typically administered as a series of intra-articular injections over several weeks.
Stem Cell Therapy
Mesenchymal stem cells can be harvested from bone marrow or adipose tissue, processed, and injected into damaged structures. These cells have the potential to differentiate into the tissue type needed for repair.
Common uses:
- Tendon injuries (particularly superficial digital flexor tendon)
- Ligament injuries (suspensory ligament)
- Joint disease
Choosing the Right Therapy
The selection of regenerative therapy depends on the specific injury, its location, chronicity, and the horse’s intended use. An experienced sports medicine veterinarian will recommend the most appropriate therapy — or combination of therapies — based on current evidence and clinical judgment.
These therapies work best as part of a comprehensive treatment plan that includes appropriate rest, controlled rehabilitation, and follow-up monitoring.